Notice (8): file_put_contents(): Write of 274 bytes failed with errno=28 No space left on device [CORE/src/Log/Engine/FileLog.php, line 140]

        if (!$mask) {
            file_put_contents($pathname, $message . "\n", FILE_APPEND);

file_put_contents - [internal], line ??
Cake\Log\Engine\FileLog::log() - CORE/src/Log/Engine/FileLog.php, line 140
Cake\Log\Log::write() - CORE/src/Log/Log.php, line 392
Cake\Log\Log::warning() - CORE/src/Log/Log.php, line 477
DebugKit\ToolbarService::isSuspiciouslyProduction() - ROOT/vendor/cakephp/debug_kit/src/ToolbarService.php, line 169
DebugKit\ToolbarService::isEnabled() - ROOT/vendor/cakephp/debug_kit/src/ToolbarService.php, line 105
DebugKit\Plugin::bootstrap() - ROOT/vendor/cakephp/debug_kit/src/Plugin.php, line 48
Cake\Http\BaseApplication::pluginBootstrap() - CORE/src/Http/BaseApplication.php, line 182
Cake\Http\Server::bootstrap() - CORE/src/Http/Server.php, line 111
Cake\Http\Server::run() - CORE/src/Http/Server.php, line 79
[main] - ROOT/webroot/index.php, line 40

Notice (8): SplFileObject::fwrite() [<a href='https://secure.php.net/splfileobject.fwrite'>splfileobject.fwrite</a>]: Write of 284 bytes failed with errno=28 No space left on device [CORE/src/Cache/Engine/FileEngine.php, line 141]

Code Context

        $success = $this->_File->ftruncate(0) &&
            $this->_File->fwrite($contents) &&
            $this->_File->fflush();

SplFileObject::fwrite() - [internal], line ??
Cake\Cache\Engine\FileEngine::set() - CORE/src/Cache/Engine/FileEngine.php, line 141
Cake\I18n\TranslatorRegistry::get() - CORE/src/I18n/TranslatorRegistry.php, line 206
Cake\I18n\I18n::getTranslator() - CORE/src/I18n/I18n.php, line 148
__ - CORE/src/I18n/functions.php, line 45
App\Controller\NewsController::view() - APP/Controller/NewsController.php, line 3420
Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 539
Cake\Controller\ControllerFactory::handle() - CORE/src/Controller/ControllerFactory.php, line 140
Cake\Controller\ControllerFactory::invoke() - CORE/src/Controller/ControllerFactory.php, line 115
Cake\Http\BaseApplication::handle() - CORE/src/Http/BaseApplication.php, line 317
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 77
Cake\Http\Middleware\CsrfProtectionMiddleware::process() - CORE/src/Http/Middleware/CsrfProtectionMiddleware.php, line 164
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 73
Cake\I18n\Middleware\LocaleSelectorMiddleware::process() - CORE/src/I18n/Middleware/LocaleSelectorMiddleware.php, line 61
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 73
Cake\Http\Middleware\BodyParserMiddleware::process() - CORE/src/Http/Middleware/BodyParserMiddleware.php, line 157
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 73

Notice (8): SplFileObject::fwrite() [<a href='https://secure.php.net/splfileobject.fwrite'>splfileobject.fwrite</a>]: Write of 91 bytes failed with errno=28 No space left on device [CORE/src/Cache/Engine/FileEngine.php, line 141]

Code Context

        $success = $this->_File->ftruncate(0) &&
            $this->_File->fwrite($contents) &&
            $this->_File->fflush();

SplFileObject::fwrite() - [internal], line ??
Cake\Cache\Engine\FileEngine::set() - CORE/src/Cache/Engine/FileEngine.php, line 141
Cake\Cache\Cache::write() - CORE/src/Cache/Cache.php, line 266
App\Controller\NewsController::action_() - APP/Controller/NewsController.php, line 6766
App\Controller\NewsController::get_data() - APP/Controller/NewsController.php, line 5701
App\Controller\NewsController::action_cache() - APP/Controller/NewsController.php, line 5625
App\Controller\NewsController::cache_action() - APP/Controller/NewsController.php, line 5281
App\Controller\NewsController::view() - APP/Controller/NewsController.php, line 3634
Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 539
Cake\Controller\ControllerFactory::handle() - CORE/src/Controller/ControllerFactory.php, line 140
Cake\Controller\ControllerFactory::invoke() - CORE/src/Controller/ControllerFactory.php, line 115
Cake\Http\BaseApplication::handle() - CORE/src/Http/BaseApplication.php, line 317
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 77
Cake\Http\Middleware\CsrfProtectionMiddleware::process() - CORE/src/Http/Middleware/CsrfProtectionMiddleware.php, line 164
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 73
Cake\I18n\Middleware\LocaleSelectorMiddleware::process() - CORE/src/I18n/Middleware/LocaleSelectorMiddleware.php, line 61
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 73

Warning (512): long cache was unable to write 'ca77a0d6b2dd67481fedef40d7b57336' to Cake\Cache\Engine\FileEngine cache [CORE/src/Cache/Cache.php, line 275]

Code Context

                ),
                E_USER_WARNING
            );

Cake\Cache\Cache::write() - CORE/src/Cache/Cache.php, line 275
App\Controller\NewsController::action_() - APP/Controller/NewsController.php, line 6766
App\Controller\NewsController::get_data() - APP/Controller/NewsController.php, line 5701
App\Controller\NewsController::action_cache() - APP/Controller/NewsController.php, line 5625
App\Controller\NewsController::cache_action() - APP/Controller/NewsController.php, line 5281
App\Controller\NewsController::view() - APP/Controller/NewsController.php, line 3634
Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 539
Cake\Controller\ControllerFactory::handle() - CORE/src/Controller/ControllerFactory.php, line 140
Cake\Controller\ControllerFactory::invoke() - CORE/src/Controller/ControllerFactory.php, line 115
Cake\Http\BaseApplication::handle() - CORE/src/Http/BaseApplication.php, line 317
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 77
Cake\Http\Middleware\CsrfProtectionMiddleware::process() - CORE/src/Http/Middleware/CsrfProtectionMiddleware.php, line 164
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 73
Cake\I18n\Middleware\LocaleSelectorMiddleware::process() - CORE/src/I18n/Middleware/LocaleSelectorMiddleware.php, line 61
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 73
Cake\Http\Middleware\BodyParserMiddleware::process() - CORE/src/Http/Middleware/BodyParserMiddleware.php, line 157

Notice (8): SplFileObject::fwrite() [<a href='https://secure.php.net/splfileobject.fwrite'>splfileobject.fwrite</a>]: Write of 130 bytes failed with errno=28 No space left on device [CORE/src/Cache/Engine/FileEngine.php, line 141]

Code Context

        $success = $this->_File->ftruncate(0) &&
            $this->_File->fwrite($contents) &&
            $this->_File->fflush();

SplFileObject::fwrite() - [internal], line ??
Cake\Cache\Engine\FileEngine::set() - CORE/src/Cache/Engine/FileEngine.php, line 141
Cake\Cache\Cache::write() - CORE/src/Cache/Cache.php, line 266
App\Controller\NewsController::action_() - APP/Controller/NewsController.php, line 6766
App\Controller\NewsController::get_data() - APP/Controller/NewsController.php, line 5701
App\Controller\NewsController::action_cache() - APP/Controller/NewsController.php, line 5625
App\Controller\NewsController::cache_action() - APP/Controller/NewsController.php, line 5281
App\Controller\NewsController::view() - APP/Controller/NewsController.php, line 3663
Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 539
Cake\Controller\ControllerFactory::handle() - CORE/src/Controller/ControllerFactory.php, line 140
Cake\Controller\ControllerFactory::invoke() - CORE/src/Controller/ControllerFactory.php, line 115
Cake\Http\BaseApplication::handle() - CORE/src/Http/BaseApplication.php, line 317
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 77
Cake\Http\Middleware\CsrfProtectionMiddleware::process() - CORE/src/Http/Middleware/CsrfProtectionMiddleware.php, line 164
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 73
Cake\I18n\Middleware\LocaleSelectorMiddleware::process() - CORE/src/I18n/Middleware/LocaleSelectorMiddleware.php, line 61
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 73

Warning (512): long cache was unable to write '1d57192e842dd84be9b2507ecd9ed207' to Cake\Cache\Engine\FileEngine cache [CORE/src/Cache/Cache.php, line 275]

Code Context

                ),
                E_USER_WARNING
            );

Cake\Cache\Cache::write() - CORE/src/Cache/Cache.php, line 275
App\Controller\NewsController::action_() - APP/Controller/NewsController.php, line 6766
App\Controller\NewsController::get_data() - APP/Controller/NewsController.php, line 5701
App\Controller\NewsController::action_cache() - APP/Controller/NewsController.php, line 5625
App\Controller\NewsController::cache_action() - APP/Controller/NewsController.php, line 5281
App\Controller\NewsController::view() - APP/Controller/NewsController.php, line 3663
Cake\Controller\Controller::invokeAction() - CORE/src/Controller/Controller.php, line 539
Cake\Controller\ControllerFactory::handle() - CORE/src/Controller/ControllerFactory.php, line 140
Cake\Controller\ControllerFactory::invoke() - CORE/src/Controller/ControllerFactory.php, line 115
Cake\Http\BaseApplication::handle() - CORE/src/Http/BaseApplication.php, line 317
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 77
Cake\Http\Middleware\CsrfProtectionMiddleware::process() - CORE/src/Http/Middleware/CsrfProtectionMiddleware.php, line 164
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 73
Cake\I18n\Middleware\LocaleSelectorMiddleware::process() - CORE/src/I18n/Middleware/LocaleSelectorMiddleware.php, line 61
Cake\Http\Runner::handle() - CORE/src/Http/Runner.php, line 73
Cake\Http\Middleware\BodyParserMiddleware::process() - CORE/src/Http/Middleware/BodyParserMiddleware.php, line 157

世界首例！科学家培育出人类体外精子

趣科技 2015-05-10 00:03:07 转载来源: 网络整理/侵权必删

医疗发展又有新突破！法国科学家声称，他们在实验室培育了人类体外精子，这是世界上第一次成功的案例，未来将可用来治疗男性不孕症。以前曾有科学家培育出健康完整的老鼠精子，但人类精子还是头一遭

医疗发展又有新突破！法国科学家声称，他们在实验室培育了人类体外精子，这是世界上第一次成功的案例，未来将可用来治疗男性不孕症。

以前曾有科学家培育出健康完整的老鼠精子，但人类精子还是头一遭。他们是从男人的睾丸中取出尚未成熟的精原细胞样本，然后变换遗传物质成为成熟的精子，并可以冷冻保存。

负责执行这个计划的法国Kallistem公司首席执行官伊莎贝尔(Isabelle Cuoc)表示：“我们的团队是世界上第一个发展可在体外完全形成精子的技术，并且有足够产量作为试管婴儿，这是一个重大的科学成果。”而目前公司计划在两年内进行人体实验，并努力筹资金，希望能带来突破性的治疗，真正造福不孕症病患。

标签: 世界首例科学家培育人类体外精子